Tomoko Doi

Tomoko Doi



Tomoko Doi


Primary department

Org1 Org2 Org3 Job title
Graduate School of Science Biological Sciences   Associate Professor

Research Topics

Study of regulated signal transduction by membrane proteins


Overview of your research

Cell surface membrane proteins transmit signals outside of the cell to the inside. Studies of the mechanisms of structure and regulation of these membrane proteins at the cellular and molecular levels are main goals of our research activities. We currently focus on the structure analysis of human endothelin type B receptor that is one of G protein-coupled receptor (GPCR) using insect-baculovirus expression system. We also study regulated signal transmission by PSD-95 which is a scaffolding protein in the postsynaptic density by utilizing a wide variety of techniques including animal models, cell systems, and molecular approaches.


Fields of research (key words)

Structural biology, Neuroscience