|Graduate School of Science||Department of Botany||Senior Lecturer|
inoue (at) cosmos.bot.kyoto-u.ac.jp
My research interests focus on understanding the development of the cellular slime mould (social amoebae) in terms of physics. The students of my research group are encouraged to find their research theme and design research projects by themselves. I also apply this principle to the one-month laboratory course for the third year undergraduate students, so taht they think with their own heads and tackle on their own small projects on whatever fields of their interest, from development to ecology.
Cellular slime moulds have two phases in their life; the growth phase as unicellular organisms, and the the mnulticellular phase in which many single cells gather together to become a multicellular tissue, which may move around like an animal ("slug"), and form the final structure called a fruiting body. Looking at such organisms, we can see fundamental features of the multicellular movement that would have remained unknown to us by research on animals alone. In addition, csm have evolved mechanisms to recognise other species to avoid mixing with them. We found that this interspecific interaction is closely related to the mechanism of multicellular movement. I think the cell sorting mechanism in organogenesis in animal development might have something in common with this.
Overview of your research
Our current projects include -
(1) Mechanis of cell movement in multicellular environment.
(2) Interspecific cell sorting ove the entire dictyostelid phylogeny.
(3) Phylogenetic comparison of differentiation regulating factors.
(4) Morphogenesis of species that make unique fruiting bodies.
(5) Diversity in temperature tolerance.
Fields of research (key words)
developmental biology, morphogenetic movement